Development of new biofabrication systems using various mechanical and electrical systems (cell-printing method, electrohydrodynamic process, 3D bioprinting, and micro/nano-imprinting method).
Tissue engineering for bone, cartilage, tympanic membrane, trachea, and liver
Experience
Chosun University, Dept. of Mechanical Eng., Assistant Professor
Korea Institute of Machinery and Materials (KIMM), Senior Researcher
Samsung Electronics, R&D Center, Senior Researcher
(2024)
Bioengineered cell-constructs using decellularized fish skin based composite bioink for regenerating muscle tissue.
APPLIED PHYSICS REVIEWS.
11,
021404
(2024)
An Approach for Fabricating Hierarchically Porous Cell-Laden Constructs Utilizing a Highly Porous Collagen-Bioink.
ADVANCED FUNCTIONAL MATERIALS.
2316222,
(2024)
Engineered 3D liver-tissue model with minispheroids formed by a bioprinting process supported with in situ electrical stimulation.
BIOACTIVE MATERIALS.
35,
(2024)
Fabrication of fully aligned self-assembled cell-laden collagen filaments for tissue engineering via a hybrid bioprinting process.
BIOACTIVE MATERIALS.
36,
(2024)
Tumor-on-a-chip models combined with mini-tissues or organoids for engineering tumor tissues.
THERANOSTICS.
14,
1
(2023)
Efficient Myogenic Activities Achieved through Blade-Casting-Assisted Bioprinting of Aligned Myoblasts Laden in Collagen Bioink.
BIOMACROMOLECULES.
24,
11
(2023)
Bioprinting 3D muscle tissue supplemented with endothelial-spheroids for neuromuscular junction model.
APPLIED PHYSICS REVIEWS.
10,
3
(2023)
Formation of various cell-aggregated structures in the core of hydrogel filament using a microfluidic device and its application as an<i> in</i><i> vitro</i> neuromuscular junction model.
CHEMICAL ENGINEERING JOURNAL.
472,
144979
(2023)
Bioprinted hASC-laden cell constructs with mechanically stable and cell alignment cue for tenogenic differentiation.
BIOFABRICATION.
15,
4
(2023)
The one-step fabrication of porous hASC-laden GelMa constructs using a handheld printing system.
NPJ REGENERATIVE MEDICINE.
8,
1
(2023)
Three-Dimensional Artificial Skin Construct Bioprinted with a Marine-Based Biocomposite.
BIOMACROMOLECULES.
24,
6
(2023)
Hierarchical fibrous collagen/poly(ε-caprolactone) structure fabricated with a 3D-printing process for tissue engineering applications.
COMPOSITES PART B-ENGINEERING.
259,
110730
(2023)
Shape-memory collagen scaffold combined with hyaluronic acid for repairing intervertebral disc.
BIOMATERIALS RESEARCH.
27,
1
(2022)
Mechanically and biologically enhanced 3D-printed HA/PLLA/dECM biocomposites for bone tissue engineering.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES.
218,
1
Patent/Intellectual Property
Surface modified polymeric nanofiber substrates by plasma-treatment and fabrication process for the same.
14/553433.
20190122.
UNITED STATES
수직 진동이 가능한 세포 프린팅용 토출장치.
10-2016-0129825.
20180314.
KOREA, REPUBLIC OF
생체 적합성이 증진된 진피대체물의 제조방법.
10-2015-0113402.
20180215.
KOREA, REPUBLIC OF
조직 재생용 인공구조체 및 이의 제조방법.
10-2015-0096774.
20170103.
KOREA, REPUBLIC OF
PCL/silica 세포지지체 제조 방법 및 이를 통해 제조된 PCL/silica 세포지지체(FABRICATION OF POLY (ε-CAPROLACTONE)/SILICA COMPOSITE SCAFFOLD).
10-1578307-0000.
20151210.
KOREA, REPUBLIC OF
세포함유 다공성 삼차원 세포담체 제조방법 및 이를 통해 제조된 세포함유 다공성.
1020140120024.
20150727.
KOREA, REPUBLIC OF
다공성 삼차원 나노섬유 세포담체 제조방법 및 이를 통해 제조된 다공성 삼차원 나노섬유 세포담체(METHOD FOR MANUFACTURING POROUS THREE-DIMENSIONAL NANOFIBROUS SCAFFOLD, AND POROUS THREE-DIMENSIONAL NANOFIBROUS SCAFFOLD MANUFACTURED BY THE METHOD).
10-1465240-0000.
20141119.
KOREA, REPUBLIC OF
조골세포 분화 촉진용 바이오리액터 시스템 및 이를 이용한 조골세포 배양 방법(BIOREACTOR SYSTEM FOR ENHANCING DIFFERENTIATION OF OSTEOBLAST, AND METHOD FOR CULTURING OSTEOBLAST USING IT).
10-1465362-0000.
20141119.
KOREA, REPUBLIC OF
플라즈마 처리에 의해 표면개질된 고분자 나노섬유 기재 및 이의 제조방법(Surface Modified Polymeric Nanofiber Substrates By Plasma-Treatment and Fabrication Process for The Same).
10-1465249-0000.
20141119.
KOREA, REPUBLIC OF
세포가 담지된 생체적합성 고분자-천연생체적합성 재료 하이브리드 구조체 및 그 제조방법.
10-2012-0111232.
20140204.
KOREA, REPUBLIC OF
Conference Paper
(2014)
Micro/nanofabrication of complex porous tissue engineering scaffolds using various 3D cell-printing methods.
2014 Burn Institute Symposium.
KOREA, REPUBLIC OF
(2014)
Effect of Micro Casting and Plasma-etching on Poly(caprolactone) Film for Bone Regeneration.
IBEC 2014 (International BioMedical Engineering Conference).
KOREA, REPUBLIC OF
(2014)
Fabrication of Collagen-coated Three-dimensional Polycaprolactone Scaffold via Melt-dispensing system and Electrohydrodynamic Process for Hard Tissue Regeneration.
IBEC 2014 (International BioMedical Engineering Conference).
KOREA, REPUBLIC OF
(2014)
Hierarchical structured surface patterns on PCL(caprolactone) fiber mat coated with collagen using a modified plasma process for tissue regeneration.
IBEC 2014 (International BioMedical Engineering Conference).
UNITED STATES
(2014)
Three-Dimensional Cell-Printed Collagen/Alginate Scaffold for Tissue Regeneration.
IBEC 2014 (International BioMedical Engineering Conference).
KOREA, REPUBLIC OF
(2014)
가교 공정을 통한 세포 함유 알지네이트 세포담채 제작 기법.
대한기계학회 바이오공학부문 추계학술대회.
KOREA, REPUBLIC OF
(2014)
에어로졸 세포 프린팅 기법을 이용한 세포가 포함된 콜라겐/알지네이트 세포담체 개발.
대한기계학회 바이오공학부문 추계학술대회.
KOREA, REPUBLIC OF
(2014)
폴리카프로락톤/알지네이트로 구성된 세포코팅 공정의 하이브리드 세포담체 제작.
대한기계학회 바이오공학부문 추계학술대회.
KOREA, REPUBLIC OF
(2014)
플라즈마 애칭을 이용한 나노 표면 구조를 가지는 마이크로 파이버 제작.
대한기계학회 바이오공학부문 추계학술대회.
KOREA, REPUBLIC OF
(2014)
Cell-laden hierarchical scaffolds consisting of solid-freeform fabricated polycaprolactone (PCL) and PCL nanofibers with cell-laden alginate struts for tissue regeneration.
ICB 2014 (International Conference of Biofabrication).
KOREA, REPUBLIC OF
(2014)
Mechanically reinforced core (PCL)-shell (collagen/alginate) hybrid scaffolds for bone tissue regeneration.
ICB 2014 (International Conference of Biofabrication).
KOREA, REPUBLIC OF
(2014)
Cell-laden hierarchical scaffolds consisting of micro-sized PCL and electrospun PCL nanofibers with cell-laden alginate struts for hard tissue regeneration.
TERMIS-AP (Tissue Engineering and Regenerative Medicine International Society).
KOREA, REPUBLIC OF
(2014)
Cell-laden poly(ε-caprolactone)/alginate hybrid scaffolds constructed for bone tissues regeneration.
TERMIS-AP (Tissue Engineering and Regenerative Medicine International Society).
KOREA, REPUBLIC OF
(2014)
Cellular interactions on hierarchically structured Poly(ε-caprolactone) (PCL) film using a combinational process (casting/plasma) for bone regeneration.
TERMIS-AP (Tissue Engineering and Regenerative Medicine International Society).
KOREA, REPUBLIC OF
(2014)
Fabrication of functionalized core/shell hybrid scaffolds for tissue engineering and regeneration.
TERMIS-AP (Tissue Engineering and Regenerative Medicine International Society).
KOREA, REPUBLIC OF
(2014)
Fabrication of three-dimensional collagen/alginate/silica composite scaffolds for hard tissue regeneration.
TERMIS-AP (Tissue Engineering and Regenerative Medicine International Society).
KOREA, REPUBLIC OF
(2014)
New cell-laden alginate scaffolds fabricated with in situ cross-linking process.
TERMIS-AP (Tissue Engineering and Regenerative Medicine International Society).
KOREA, REPUBLIC OF
(2014)
Novel electrohydrodynamic printing method for controlling 3D fibrous construct consisted of micro/nanofibers as a tissue regenerative material: Fabrication and cellular activities.
TERMIS-AP (Tissue Engineering and Regenerative Medicine International Society).
KOREA, REPUBLIC OF
(2014)
Novel electrohydrodynamic process for fabrication of highly porous 3D micro/nanofibrous scaffolds.
TERMIS-AP (Tissue Engineering and Regenerative Medicine International Society).
KOREA, REPUBLIC OF
(2014)
The effect of hierarchical structure of Poly(ε -caprolactone) (PCL) film using a combinational process (casting/plasma) on cellular responses.
TERMIS-EU (Tissue Engineering and Regenerative Medicine International Society).
ITALY